Diabetes mellitus

Abstract

Tato diplomová práce se zaměřila na popis diabetes mellitus z hlediska patogeneze, rizikových komplikací, farmakologické a nefarmakologické léčbě. Kormě toho jsme se v této diplomové práci také zaměřili na vztah diabetes mellitus a Alzheimerova nemoc. U tohoto stavu dochází k poruchám metabolizmu cukru, čím dochází k poškození činnosti mozku což může přispívat také k rozvoji a progresi Alzheimerovy choroby.

This theses on Diabetes Mellitus aims at giving an insight at various aspects of this chronic disease and the risk factors that lead to it; the varius ways it develops in the human body; the old and new approaches to treatment, both from a pharmacological and a non- pharmacologiacal point of view; ways to prevent and to manage the diabetes complications; how to improve the live of the diabetic patients who are faced with not only physical but also psychological problems; statistical data from around the world wkich focuses on epidemiology and outlines the issue of the cost of diabetes. Finally, this paper links diabetes mellitus with the Alzheimer's disease as a different expression of diabetes, since it is closely associated with several key neuronal factors implicated in dementia. In many respects, Alzheimer's is a brain form of diabetes. Even in the earliest stages of the disease, the brain's ability to metabolize sugar is reduced. Normally, insulin plays a big role in helping the brain take up sugar from the blood. But, in Alzheimer's, insulin is not very effective in the brain. Consequently, the brain cells practically starve to death.