| dc.contributor.advisor | Černá, Marie | |
| dc.creator | Douglas, James Joshua | |
| dc.date.accessioned | 2018-09-12T10:43:33Z | |
| dc.date.available | 2018-09-12T10:43:33Z | |
| dc.date.issued | 2007 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.11956/8110 | |
| dc.description.abstract | The continued understanding of gene structure, function and how its product interacts in the human body has lead to new wave of ideas on cancer therapy. Gene therapy, which 20 years ago was just a dream is now a very real possibility and alternative to the conventional treatments. Three new methods of utilizing alternative gene structure and manipulating the body's response to induce a tumor effect are presented here. Immunotherapy is the induction of the human immune system against an unwanted antigen. Viral oncolysis is the utilization and manipulation of natural human pathogens against tumor cells. Gene transfer is the addition of deletion of vital genes responsible for cell growth and apoptosis. | en_US |
| dc.language | English | cs_CZ |
| dc.language.iso | en_US | |
| dc.publisher | Univerzita Karlova, 3. lékařská fakulta | cs_CZ |
| dc.title | Gene Therapy and the Evolution of Cancer Treatment | en_US |
| dc.type | diplomová práce | cs_CZ |
| dcterms.created | 2007 | |
| dcterms.dateAccepted | 2007-04-04 | |
| dc.description.department | Ústav biochemie, buněčné a molekulární biologie | cs_CZ |
| dc.description.department | Department of Biochemistry, Cell and Molecular Biology | en_US |
| dc.description.faculty | Third Faculty of Medicine | en_US |
| dc.description.faculty | 3. lékařská fakulta | cs_CZ |
| dc.identifier.repId | 13899 | |
| dc.title.translated | Genová terapie a pokrok v léčbě rakoviny | cs_CZ |
| dc.identifier.aleph | 000980047 | |
| thesis.degree.name | MUDr. | |
| thesis.degree.level | magisterské | cs_CZ |
| thesis.degree.discipline | - | cs_CZ |
| thesis.degree.discipline | - | en_US |
| thesis.degree.program | General Medicine | en_US |
| thesis.degree.program | Všeobecné lékařství | cs_CZ |
| uk.thesis.type | diplomová práce | cs_CZ |
| uk.taxonomy.organization-cs | 3. lékařská fakulta::Ústav biochemie, buněčné a molekulární biologie | cs_CZ |
| uk.taxonomy.organization-en | Third Faculty of Medicine::Department of Biochemistry, Cell and Molecular Biology | en_US |
| uk.faculty-name.cs | 3. lékařská fakulta | cs_CZ |
| uk.faculty-name.en | Third Faculty of Medicine | en_US |
| uk.faculty-abbr.cs | 3.LF | cs_CZ |
| uk.degree-discipline.cs | - | cs_CZ |
| uk.degree-discipline.en | - | en_US |
| uk.degree-program.cs | Všeobecné lékařství | cs_CZ |
| uk.degree-program.en | General Medicine | en_US |
| thesis.grade.cs | Výborně | cs_CZ |
| thesis.grade.en | Excellent | en_US |
| uk.abstract.en | The continued understanding of gene structure, function and how its product interacts in the human body has lead to new wave of ideas on cancer therapy. Gene therapy, which 20 years ago was just a dream is now a very real possibility and alternative to the conventional treatments. Three new methods of utilizing alternative gene structure and manipulating the body's response to induce a tumor effect are presented here. Immunotherapy is the induction of the human immune system against an unwanted antigen. Viral oncolysis is the utilization and manipulation of natural human pathogens against tumor cells. Gene transfer is the addition of deletion of vital genes responsible for cell growth and apoptosis. | en_US |
| uk.file-availability | V | |
| uk.publication.place | Praha | cs_CZ |
| uk.grantor | Univerzita Karlova, 3. lékařská fakulta, Ústav biochemie, buněčné a molekulární biologie | cs_CZ |
| thesis.grade.code | 1 | |
| dc.identifier.lisID | 990009800470106986 | |
