Přírodovědecká fakulta: Poslední příspěvky
Zobrazují se záznamy 1-20 z 29753
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Study of the substrate specificity of the LACTB tumour suppressor enzyme
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2019)Datum obhajoby: 19. 9. 2019Serine beta-lactamase-like protein (LACTB) is a tumour suppressor that modulates mitochondrial lipid metabolism and induces differentiation of breast cancer cells. This is achieved by the LACTB-dependent downregulation of ... -
Ecology of bryophytes in post mining sites
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2023)Datum obhajoby: 22. 5. 2023Mining sites offer a mosaic of spoil heaps of different age, with diverse substrate characteristics. Especially problematic for vegetation development can be toxic spoil heaps with substrate from the Tertiary rocks ... -
Classification of global environmental systems according to the level of anthropogenic transformation
Výsledek obhajoby: UZNÁNO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 26. 4. 2024The topic of the doctoral thesis is the development of a comprehensive classification of global environmental systems based on a geographical synthesis of abiotic, biotic and anthropogenic factors. The dramatic changes in ... -
Changes in rainfall-runoff regime and biogeochemistry in headwater areas
Výsledek obhajoby: UZNÁNO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 26. 4. 2024Headwater areas are a very important current or potential drinking water source. Their ecological value for the whole ecosystem is equally important. Headwater areas are sites with minimal anthropogenic intervention and ... -
Lower Cretaceous belemnites (including J/K boundary interval) in the NW Tethys, biostratigraphy, palaeobiogeography and palaeoecology
Výsledek obhajoby: UZNÁNO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 25. 4. 2024This thesis deals with the belemnite fauna from the Outer Western Carpathians Klippen, its systematic classification, stratigraphical and palaeogeographical evaluation. The palaeontological/palaeobiological approach, ... -
Molekulárně-genetická analýza karcinomů štítné žlázy u dětských a dospívajících pacientů
Výsledek obhajoby: UZNÁNO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 22. 4. 2024Thyroid nodules are rare in pediatric and adolescent patients, but they are at greater risk of malignancy than adult patients. Thyroid carcinomas are the most common endocrine malignancy and their incidence is increasing. ... -
Studying the dynamics of gene expression and the role of NAC complex in male gametophyte development
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 22. 3. 2024This Ph.D. thesis presents a comprehensive study of gene expression regulation within the male gametophyte development focusing on transcriptional, translational, and post- translational levels. The research introduces an ... -
Evolution of Host Specialisation, Phylogeography and Taxonomic Revision of Xenidae (Strepsiptera)
Výsledek obhajoby: UZNÁNO(Univerzita Karlova, Přírodovědecká fakulta, 2023)Datum obhajoby: 19. 12. 2023Twisted-winged parasites (Strepsiptera: Xenidae) are an excellent group for studying the specialisation of parasites on hosts. Their parasitic lifestyle led to the evolution of numerous morphological, behavioural, ... -
Hydrofilná interakčná kvapalinová chromatografia v analýze intaktných glykopeptidov
Výsledek obhajoby: UZNÁNO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 29. 4. 2024The analysis of glycoproteins represents a significant challenge in glycoproteomics, primarily due to the macro- and microheterogeneity of protein glycosylation. Hydrophilic interaction liquid chromatography (HILIC) is a ... -
Structural studies of an abasic site DNA damage repair and DNA interstrand cross-link formation
Výsledek obhajoby: UZNÁNO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 23. 4. 2024DNA damage refers to any alteration or modification in the DNA structure that deviates from its natural state. Abasic site (Ap site) is one of the most common DNA lesions resulting from spontaneous depurination/depyrimidination ... -
Relationship between perceptual and structural variation of human faces: cross-cultural comparison
Výsledek obhajoby: UZNÁNO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 15. 4. 2024ONDŘEJ PAVLOVIČ RELATIONSHIP BETWEEN PERCEPTUAL AND STRUCTURAL VARIATION OF HUMAN FACES: CROSS- CULTURAL COMPARISON ABSTRAKT The perception of facial features is a fundamental aspect of human culture, influencing daily ... -
Mechanisms of the tolerance and homeostasis of immune cells
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2022)Datum obhajoby: 29. 4. 2022The ability of the immune system to tolerate self-antigens while mounting appropriate responses to pathogens is indispensable for the survival of the organism. Despite years of research, many details of the mechanisms of ... -
Diverzita vybraných skupin střevních prvoků u švábů (Blattodea bez Isoptera)
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 26. 3. 2024This thesis addresses the rather neglected diversity of protists inhabiting the anoxic environment of the hindgut of cockroaches (Blattodea excluding Isoptera). I have examined the composition of the eukaryotic hindgut ... -
Evolutionary Aspects of the Human Aesthetic Responses to Flowers
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2023)Datum obhajoby: 18. 12. 2023Human aesthetic responses to plants and flowers have long been an unexplored topic in people-plant interactions research. Theories focusing on aesthetic responses to plants and studies testing the effects of plants on human ... -
A study of non-volatile nitroso compounds in brewing
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 16. 2. 20244 Abstract Nitroso compounds are beer contaminants related to carcinogenicity and can be naturally formed during brewing. They are generally categorized as volatile and non-volatile. Well-characterized and proven carcinogenic ... -
Dynamika rezidenční diferenciace a segregace cizinců v metropolitních areálech Česka
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 26. 3. 2024Czechia has become a noteworthy case study of international migration within Central and Eastern Europe. With a steadily increasing inflow of international migrants, it is anticipated that their contribution to the societal ... -
Hydrofilná interakčná kvapalinová chromatografia v analýze intaktných glykopeptidov
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 22. 3. 2024The analysis of glycoproteins represents a significant challenge in glycoproteomics, primarily due to the macro- and microheterogeneity of protein glycosylation. Hydrophilic interaction liquid chromatography (HILIC) is a ... -
Atomic fluorescence spectrometry with volatile species generation - a sensitive tool for ultra-trace elemental analysis
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 16. 2. 2024This thesis encompasses a development of innovative methodologies based on atomic fluorescence spectrometry, offering precise and sensitive determination of ultra-trace elements, such as bismuth, cadmium, and nickel. The ... -
Tracing Microendolithic Ichnocenoses: A paleoecological and taphonomic approach over the Phanerozoic
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 26. 3. 2024The microbial endoliths study from the Western Carpathians region was a semi-quantitative survey that included six sampling localities. Samples, ranging from Upper Oligocene to Miocene (Serravalian), came from three ... -
Vliv nabídky stravovacích zařízení na environmentálně udržitelný rozvoj cestovního ruchu
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 26. 3. 2024Food accompanies a tourist's stay in a destination from the very beginning to the very end and significantly influences the overall travel experience. However, gastronomic experiences also have a significant impact on the ...