Cíle: Cílem této diplomové práce bylo porovnat podíl příčin náhlých srdečních zástav v závislosti na věku, zkoumat podíl kardiálních náhlých srdečních zástav v závislosti na pohlaví a analyzovat vliv věku na pravděpodobnost ...

Aktivace N-methyl-D-aspartátového receptoru (NMDAR) vede skrze intracelulární signální kaskády k modulaci funkční a strukturní plasticity, a sehrává tak zásadní roli v kognitivních procesech jako je učení a paměť. Poruchy ...

Background: One of the most common clinical manifestations of multiple sclerosis is foot drop syndrome, which significantly affects the gait and balance of people with multiple sclerosis (MS). Functional electrical stimulation ...

1 ABSTRACT Introduction: The incidence of head and neck squamous cell carcinoma (HNSCC) is on a continuous increasing trend worldwide, despite known risk factors and primary prevention of the disease. Secondary prevention ...

Background: Considerable number of patients suffering from depression (unipolar or bipolar) does not reach a relief undergoing pharmacological or psychotherapeutic treatments available. There is a need for a new treatment ...

A randomized comparison of His bundle pacing versus RV pacing: effect on left ventricular function and biomarkers of collagen metabolism Background: Right ventricular pacing (RVP) may result in pacing-induced cardiomyopathy ...

1 SUMMARY Obesity and overfeeding are associated not only with increased circulating levels of nutrients and metabolites, but also with increased risk of the development of additional disorders, such as cardiovascular ...

Acute leukemias (AL) comprise a heterogeneous group of hematologic malignancies, and individual patient responses to treatment can be difficult to predict. Monitoring of minimal residual disease (MRD) is thus very important ...

This project has shown that pelvic organ prolapse is linked with maternal age and delivery-related injuries. Up to every eight women may have a symptomatic prolapse already one year after their first delivery. Moreover, ...

Keywords Burn shock; fluid therapy; arterial pulse contour analysis; dynamic preload parameters; hourly urine output. Introduction: Our hypothesis is based on the assumption that ...

Preterm neonate is exposed to significant hemodynamic changes after delivery. Cardiac and extracardiac shunts, especially ductus arteriosus, play an important role in this process. Failure of postnatal adaptation and ...

Intraarticular bleeding is a complication, that concerns almost every person with haemophilia. The number and heaviness of them depends on the grade of illness and on presence of inhibitor. Presence of blood inside joint ...

Background. The analysis of the current approaches to antithrombotic treatment of cardiac patients in the perioperative period of major non-cardiac surgery was performed. The incidence of ischemic and bleeding complications ...

Adipose tissue (AT) is a complex organ specialised in safe storage and release of energy as lipids. The adipose organ is therefore essential for the maintenance of energy homeostasis. The prototypical cells of AT are ...

Obstetrical brachial plexus palsy (OBPP) displays a stable incidence of 0.15 - 3 per 1,000 live births. Most children show good spontaneous recovery, but a recent literature reviews show that a residual deficit remains in ...

The alternation of light and darkness,caused by the Earth's rotation around its axis, is one of the significant factorsinfluencing life on our planet. This cycle is so fundamental that it has affectedthe evolutionary ...

This Thesis discusses the complex topic of the role of proteinase-activated receptors (PARs) in the physiology and pathophysiology of central nervous system diseases, and to some extent, the role of PARs in cancer pathobiology. ...

The dissertation is focused on the problem of visual perception and its dis- turbance in patients with schizophrenia. The relationship between dopaminergic transmission at the retinal level and its possible association ...