Ventilátorová pneumonie, ventilator-associated pneumonia (VAP), je nejčastější nemocniční infekcí na jednotkách intenzivní péče. Rozvíjí se po více než 48 hodinách od připojení na umělou plicní ventilaci. Jedná se o závažnou ...

In terms of loss of independence, mortality and their economic impact, proximal femoral fractures are the most serious of all low energy fractures. They heighten the risk of further low energy fractures including contralateral ...

Women, who abuse drugs during pregnancy, expose not just themselves but also their developing foetus to impairing effects, which can have potentially harmful and even long- term effects on the exposed children. For some ...

Univerzita Karlova v Praze 3. lékařská fakulta Treatment of acute myocardial infarction in the era of percutaneous coronary intervention MUDr. Jiří Knot 2014 When treating patients with acute myocardial infarction (AMI), ...

Vertebrobasilar ischemic strokes, caused by lesions of magistral arteries. Background and Purpose Progress in modern non-invasive or minimally invasive diagnostic methods has improved detection and evaluation of pathological ...

Present the dissertation thesis on the topic "The use of a capillary electrophoresis and electrophoresis on chip for clinical research" is divided into two separate parts. The first chapter summarizes the problems of ...

The present thesis deals with the electrophysiological and behavioral correlates of the effects of serotonergic psychedelics in an animal model of psychosis. In the general part, we describe the phenomenology and neurobiology ...

Aortic stenosis (AS) and mitral regurgitation (MR) are the most common valvular heart diseases in the adult population. Additionally, they are the most likely to need surgical intervention. Treatment preceding surgical or ...

Univerzita Karlova v Praze, 3. lékařská fakulta Disertační práce MUDr. Vladimír Řihák Kondenzát vydechovaného vzduchu v diagnostice plicních nemocí Breath condensate in the diagnostics of lung diseases Školitel: doc. MUDr. ...

Obstetrical brachial plexus palsy (OBPP) displays a stable incidence of 0.15 - 3 per 1,000 live births. Most children show good spontaneous recovery, but a recent literature reviews show that a residual deficit remains in ...

This Thesis discusses the complex topic of the role of proteinase-activated receptors (PARs) in the physiology and pathophysiology of central nervous system diseases, and to some extent, the role of PARs in cancer pathobiology. ...

Ventricular assist devices are an important therapeutic modality in advanced surgical therapy of end-stage heart failure. Devices mainly used until recently generate primarily non- pulsatile blood flow. Despite indisputable ...

(EN) Type 1 diabetes (T1D) belongs among polygenic multifactorial autoimmune diseases. The highest risk is associated with HLA (human leukocyte antigen) class II genes, including HLA-DQA1 gene. Our aim was to investigate ...

The presented work focuses on the animal models of schizophrenia. The general part is dedicated to describing histomorphological and biochemical changes in patients with schizophrenia and basic classification and description ...

1 ABSTRACT In the Czech Republic a complex study of adverse reactions after vaccination in children has not been presented yet. Even though reporting of serious adverse reactions to the State Institute for Drug Control ...

Ankle fractures can be serious and complex injuries with variable prognoses. In our department, ankle fractures are the third most common fracture behind fractures of the distal radius and the proximal femur. Ankle fractures ...

Cardiac arrest is an extremely serious condition characterized by global ischemia followed by reperfusion after successful resuscitation and restoration of spontaneous circulation. Despite all advances in current medicine, ...

In the last decade, there is a growing focus of health professionals on growth of children and their mode of feeding in the early age. According to the WHO global public health recommendation, infants should be exclusively ...

Skeletal muscle plays an important role in the maintenance of whole-body metabolic homeostasis. Metabolic alterations of skeletal muscle contribute to the pathogenesis of a wide range of human diseases, such as obesity, ...

The present work describes animal models of psychosis with the aim on monoamine levels and behavioral/EEG findings. The general part is focused on reporting biochemical and EEG findings in patients with schizophrenia, ...

Background: Periprocedural bleeding is the most common complication related to coronary angiography (CAG) and percutaneous coronary intervention (PCI) and it is associated with worse short-term and long-term prognosis. ...

Introduction: Impairment of intestinal barrier function is involved in pathogenesis of immune mediated diseases (such as type 1 diabetes mellitus or celiac disease) and metabolic diseases (such as type 2 diabetes mellitus). ...

Background: The ischemic-reperfusion injury represents an important preventable factor, due to its essential impact on prognosis of patients with acute myocardial infarction (AMI). One of the most important modifiers of ...

Spatial memory is often studied using spatial tasks originally developed for animals, such as the Morris water maze and the Carousel maze tasks. Both tasks have an important role in the process of identification of brain ...

Our work is composed of part done on laboratory rat, part done on magnetic resonance images and autoptic CNS tissue in patients with Alzheimer's disease (AD) and control group. In the first part we observed volumetrically ...

Hypertrofická kardiomyopatie (HKMP) je onemocnění myokardu, které vzniká v důsledku mutací v genech kódujících bílkoviny sarkomery srdečního svalu. Je charakteristická nejenom širokou genotypovou, ale i širokou fenotypovou ...